Prediction of tolerance in children with IgE mediated cow's milk allergy by microarray profiling and chemometric approach

A new protocol for specific oral tolerance induction in children with IgE-mediated cow's milk allergy.

IgE-mediated cow's milk allergy (CMA) is a heavy burden for patients, particularly for children and their families. Allergen avoidance represents the only therapeutic option, but oral desensitization protocols have been suggested. Because of the long duration and complexity of these protocols we examined the feasibility of an oral tolerance induction protocol using a weekly up-dosing schedule. ...

Egg and cows' milk allergy in children.

The relationships between a history of egg or cows' milk allergy, positive skin tests to these allergens, and atopic illness were examined in a sample of 126 children. Positive skin tests were found more often in children with a history of egg or cows' milk allergy than in children with no such history. 40 children suspected of being allergic to egg or milk, by history or by positive skin tests...

Prediction of Lipophilicity and Pharmacokinetics of Chloroacetamides by Chemometric Approach

In this study, the existence of biological potential of selected N-(substituted phenyl)-2-chloroacetamides was examined none empirically, as was the possibility of applying simpleexperimental technique in predicting essential properties which affect the biological activityof the compounds. By applying the Lipinski and Ghose’s rules, it has been revealed that theexamined chloroacetamides fulfill...

Managing cows' milk allergy in children.

[Non IgE-mediated cow's milk allergy].